Robert Arking's Biology of Aging: Observations and Principles PDF
By Robert Arking
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Extra resources for Biology of Aging: Observations and Principles
This method often helps us grasp the unfamiliar, but it can lead us into difficulties. Humans and the various domesticated animals with which we are familiar age in a similar manner. After a developmental period that culminates in sexual maturity, adults maintain physical vigor for a relatively long time before beginning to manifest progres- sive dysfunctions in various physiological systems over a relatively extended period of time. Despite the substantial differences in absolute life span, the pattern of aging in humans, dogs, cats, horses, mice, and other placental mammals follows this progression.
The animal contains the mechanisms necessary to bring about at least three different extended longevity phenotypes; the nature of the environmental signal specifies which one is actually expressed. Both chance and signal specificity contribute to the plasticity of the longevity phenotype. An example of phenotypic plasticity in which we have at least partly defined one of the environmental parameters and its interaction with a particular genotype is the case of the F344 rat and its diet, as described earlier.
Students are entitled to a highly discounted 6-month membership. sageke/crossroads) deals with the ethical, social, and political debates now taking place in the larger community, and this site may be particularly informative when reading chapter 15. 6 To help understand the aging process, the life span of gradually aging animals such as humans can be viewed as composed of two interdigitating phases. The health span begins at the end of development and ends when the age-dependent mortality rate begins to increase significantly.
Biology of Aging: Observations and Principles by Robert Arking